Markgraf, Carrie G.: search on Z-Library

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1

Twenty years of safety pharmacology model validation and the wider implications of this to drug discovery

Pugsley, Michael K., Bekele, Bisrat, Griessel, Helene, de Korte, Tessa, Authier, Simon, Grobler, Anne F., Markgraf, Carrie G., Curtis, Michael J.

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2020

File:

PDF, 1.51 MB

2020

2

Validation of a motor activity system by a robotically controlled vehicle and using standard reference compounds

John P. Patterson, Carrie G. Markgraf, Maria Cirino, Alan S. Bass

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2005

Language:

english

File:

PDF, 403 KB

english, 2005

3

Overview of the joint PhRMA-FDA dialogue session on abuse potential assessment

Carrie G. Markgraf, Mary Jeanne Kallman

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2009

Language:

english

File:

PDF, 68 KB

english, 2009

4

EEG in non-clinical drug safety assessments: Current and emerging considerations

Authier, Simon, Delatte, Marcus S., Kallman, Mary-Jeanne, Stevens, Joanne, Markgraf, Carrie

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2016

Language:

english

File:

PDF, 810 KB

english, 2016

5

An Overview of the Safety Pharmacology Society (SPS) Strategic Plan (2016-2018)

Pugsley, Michael K., Authier, Simon, Koerner, John, Redfern, Will S., Markgraf, Carrie G., Brabham, Tiffini, Correll, Krystle, Soloviev, Maxim, Botchway, Alfred, Engwall, Michael, Traebert, Martin, Va

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2017

Language:

english

File:

PDF, 42 KB

english, 2017

6

Abuse potential assessment of preladenant, an adenosine2A receptor antagonist: Self-administration in rats

Briscoe, Richard, Markgraf, Carrie, Gauvin, David, Rosenfeld, Clint

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2015

Language:

english

File:

PDF, 49 KB

english, 2015

7

Ibotenic acid lesions in the amygdaloid central nucleus but not in the lateral subthalamic area prevent the acquisition of differential Pavlovian conditioning of bradycardia in rabbits

Philip M. McCabe, Christopher G. Gentile, Carrie G. Markgraf, Alan H. Teich, Neil Schneiderman

Journal:

Year:

1992

Language:

english

File:

PDF, 1.04 MB

english, 1992

8

Hypothalamic, midbrain and bulbar areas involved in the defense reaction in rabbits

Carrie G. Markgraf, Ray W. Winters, David R. Liskowsky, Philip M. McCabe, Edward J. Green, Neil Schneiderman

Journal:

Physiology & Behavior

Year:

1991

Language:

english

File:

PDF, 913 KB

english, 1991

9

Assessment of seizure liability of Org 306039, a 5-HT2c agonist, using hippocampal brain slice and rodent EEG telemetry

Markgraf, Carrie, DeBoer, Erik, Zhai, Jin, Cornelius, Lara, Zhou, Ying Ying, MacSweeney, Cliona

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2015

Language:

english

File:

PDF, 53 KB

english, 2015

10

Injury Severity and Sensitivity to Treatment After Controlled Cortical Impact in Rats

Markgraf, Carrie G., Clifton, Guy L., Aguirre, Michela, Chaney, Stephan F., Knox-Du Bois, Cami, Kennon, Katherine, Verma, Nishi

Journal:

Journal of Neurotrauma

Year:

2001

Language:

english

File:

PDF, 232 KB

english, 2001

11

Treatment window for hypothermia in brain injury

Markgraf, Carrie G., Clifton, Guy L., Moody, Melanie R.

Journal:

Journal of Neurosurgery

Year:

2001

Language:

english

File:

PDF, 182 KB

english, 2001

12

Abuse potential assessment of preladenant, an adenosine2a receptor antagonist: Drug discrimination in rats

Markgraf, Carrie, Briscoe, Richard, Gauvin, David, Rosenfeld, Clint

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2015

Language:

english

File:

PDF, 71 KB

english, 2015

13

Comparison of methods for analysis of functional observation battery (FOB) data

Carrie G. Markgraf, Maria Cirino, John Meredith

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2010

Language:

english

File:

PDF, 173 KB

english, 2010

14

Assessment of seizure liability of Org 306039, a 5-HT2c agonist, using hippocampal brain slice and rodent EEG telemetry

Markgraf, Carrie G., DeBoer, Erik, Zhai, Jin, Cornelius, Lara, Zhou, Ying Ying, MacSweeney, Cliona

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2014

Language:

english

File:

PDF, 515 KB

english, 2014

15

Behavioral Recovery Patterns in Rats Receiving the NMDA Receptor Antagonist MDL 100,453 Immediately Post-Stroke

Carrie G Markgraf, Michael P Johnson, Don L Braun, Mary V Bickers

Journal:

Pharmacology Biochemistry and Behavior

Year:

1997

Language:

english

File:

PDF, 208 KB

english, 1997

16

Response variation in instrumental extinction in rats with fornix transections

Bob Osborne, Carrie Markgraf

Journal:

Behavioral and Neural Biology

Year:

1988

Language:

english

File:

PDF, 640 KB

english, 1988

17

MDL 101,002, a free radical spin trap, is efficacious in permanent and transient focal ischemia models

Michael P Johnson, Debbie R McCarty, Nelson L Velayo, Carrie G Markgraf, Paula A Chmielewski, James V Ficorilli, Hsien C Cheng, Craig E Thomas

Journal:

Year:

1998

Language:

english

File:

PDF, 942 KB

english, 1998

18

Abuse potential assessment of preladenant, an adenosine2a receptor antagonist: Physical discrimination in rats

Markgraf, Carrie, Briscoe, Richard, Gauvin, David, Rosenfeld, Clint

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2015

Language:

english

File:

PDF, 48 KB

english, 2015

19

Sensorimotor and cognitive consequences of middle cerebral artery occlusion in rats

Carrie G. Markgraf, Edward J. Green, Barry E. Hurwitz, Eiharu Morikawa, W. Dalton Dietrich, Philip M. McCabe, Myron D. Ginsberg, Neil Schneiderman

Journal:

Year:

1992

Language:

english

File:

PDF, 2.86 MB

english, 1992

20

The Safety Pharmacology Society salary survey

Pugsley, Michael K., Authier, Simon, Brabham, Tiffini, Soloviev, Maxim, Markgraf, Carrie G., Correll, Krystle, Traebert, Martin, Greiter-Wilke, Andrea, Valentin, Jean-Pierre, Vargas, Hugo, Botchway, A

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2017

Language:

english

File:

PDF, 1.56 MB

english, 2017

21

Benchmarking Safety Pharmacology regulatory packages and best practice

Silvana Lindgren, Alan S. Bass, Richard Briscoe, Kristy Bruse, Gregory S. Friedrichs, Mary Jeanne Kallman, Carrie Markgraf, Leslie Patmore, Michael K. Pugsley

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2008

Language:

english

File:

PDF, 355 KB

english, 2008

22

Effects of fornix transection and pituitary-adrenal modulation on extinction behavior.

Osborne, Bob, Silverhart, Todd, Markgraf, Carrie, Seggie, Jo

Journal:

Behavioral Neuroscience

Year:

1987

Language:

english

File:

PDF, 958 KB

english, 1987

23

EEG in monkey but not rat indentifies seizure potential of a pharmaceutical development candidate

Carrie G. Markgraf, Erik M. DeBoer, Maria Cirino

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2010

Language:

english

File:

PDF, 64 KB

english, 2010

24

Neurobehavioral contributions to cardiac arrhythmias during aversive pavlovian conditioning in the rabbit receiving digitalis

Carrie G. Markgraf, Bruce S. Kapp

Journal:

Journal of the Autonomic Nervous System

Year:

1988

Language:

english

File:

PDF, 2.10 MB

english, 1988

25

Abuse liability assessment for biologic drugs – All molecules are not created equal

Zuch de Zafra, Christina L., Markgraf, Carrie G., Compton, David R., Hudzik, Thomas J.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2017

Language:

english

File:

PDF, 571 KB

english, 2017

26

Glutamate antagonist MK-801 attenuates incomplete but not complete infarction in thrombotic distal middle cerebral artery occlusion in Wistar rats

Hiroshi Yao, Carrie G. Markgraf, W. Dalton Dietrich, Ricardo Prado, Brant D. Watson, Myron D. Ginsberg

Journal:

Year:

1994

Language:

english

File:

PDF, 1.73 MB

english, 1994

27

Is there a role for the no observed adverse effect level in safety pharmacology?

Mow, Tomas, Andersen, Ninette K., Dragsted, Nils, Lassen, Anders B., Laursen, Morten, Bass, Alan S., Valentin, Jean-Pierre, Markgraf, Carrie, Authier, Simon, Baird, Theodore J., Bhatt, Siddhartha, Tra

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2020

File:

PDF, 663 KB

2020

28

Lesions of the amygdaloid central nucleus block conditioned cardiac arrhythmias in the rabbit receiving digitalis

Carrie G. Markgraf, Bruce S. Kapp

Journal:

Journal of the Autonomic Nervous System

Year:

1991

Language:

english

File:

PDF, 878 KB

english, 1991

29

Safety pharmacology investigations on the nervous system: An industry survey

Authier, Simon, Arezzo, Joseph, Delatte, Marcus S., Kallman, Mary-Jeanne, Markgraf, Carrie, Paquette, Dominique, Pugsley, Michael K., Ratcliffe, Sian, Redfern, William S., Stevens, Joanne, Valentin, J

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2016

Language:

english

File:

PDF, 825 KB

english, 2016

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